PhD Candidate (Dr. rer. nat) - Biological Data Science

"Knowledge becomes health" - we are filling this motto with life every day, developing new ideas and improv-ing old-established knowledge. The University Hospital Frankfurt has existed since 1914. Our around 8,500 employees contribute with their skills and knowledge to the 32 specialist clinics, theoretical clinical institutes, and administrative departments. The close connection of health care with research and teaching, as well as a climate of collegiality, internationality, and cross-professional cooperation characterize the university hospital.

PhD Candidate (Dr. rer. nat) - Biological Data Science

(We are targeting applicants of all genders)
Full time | limited up to 3 years | Announcement number: 612-2024

The M olecular Genetics Laboratory at the Department for Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy in Frankfurt is a leader in research into the genetic causes of neuropsychiatric disorders. Using state-of-the-art technologies such as multimodal machine learning, genome-wide analysis methods and neuronal cell models, the team investigates genetic variations and mechanisms that contribute to autism, ADHD or social conduct disorders. Through interdisciplinary collaboration and international cooperation, the laboratory combines genetic data with clinical information in order to develop new diagnostic and therapeutic approaches.

About the project

The position is part of the Transregional Collaborative Research Center TRR 379 Neuropsychobiology of Aggression . The aim is to identify multidimensionally defined biosignatures of aggression in mental disorders. These will then be used to develop customized, biomarker-driven prevention and intervention measures. In sub-project C04, this is being investigated in adolescents. The focus is on the role of risk-moderating factors and biosignatures on aggression in mental disorders. The project primarily draws on previously collected data and biosamples (genetics, hormones, clinical data).

As part of your work, you will be integrated into an international network that offers a structured, extended curriculum and not only connects many young researchers, but also includes workshops, training courses, a lecture series and the possibility of a laboratory rotation.

The doctoral position is embedded transregionally and in cooperation with the University of Frankfurt, RWTH Aachen University, the University of Heidelberg, the Central Institute of Mental Health as well as the Universities of Mainz, Würzburg and Forschungszentrum Jülich. The TRR/SFB 379 is funded by the German Research Foundation (DFG). Further information on the TRR and subproject C04 can be found at https://trr379.de/projects/c04/ . Information on the working group can be found at https://chiocchettilab.uni-frankfurt.de .

Your role

Scientific work with the aim of a publication-based doctorate
Programming-based preparation and processing of biological and clinical data
Support of ongoing recruitment from the data side, database management, data entry
Further development of an analysis pipeline for feature generation and biostatistical analysis
Data-driven analysis of the questions
Publication of the results in scientific journals
Presentation and discussion of the project and research results at specialist conferences in Germany and abroad
Coordination and networking with the other TRR centers
Supervision of interns and Bachelor's/Master's students
Organizational tasks within the framework of the project

Who you are

You have successfully completed a university degree (Master of Science) in a natural science field.
Good knowledge of genetic analysis is desirable.
Skills in programming-based data processing (e.g. R, Python) with a basic understanding of machine learning are required
Knowledge in the fields of psychiatry or psychology is desirable
You have already gained experience in scientific work as part of your studies.
You are motivated and curious to try out new things
Good knowledge of German (min. B2) and very good knowledge of English (C1) are expected.
Due to legal regulations, valid proof of measles immunity / measles vaccination is required.

What we offer

Working environment: Working in an international, interdisciplinary and renowned research team. Agile working methods and flat hierarchies. We live psychological safety and value respect, recognition and diversity.

Mobile working: A large part of the tasks can also be performed remotely, whereby regular on-site appointments and a basic willingness to travel are expected.

Collective agreement: In addition to an attractive salary based on a collective agreement (65% E13) with an annual special payment, you benefit from long-term security through company pension schemes

Mobility: Free public transport in all Hessen (Free State Ticket Hessen)

Campus: Our attractive university hospital campus offers a modern cafeteria, various cafes, and opportunities to rest in numerous green spaces. A walk on the riverside of the Main offers relaxation during breaks

Work-Life-Balance: Part-time employment is possible, we offer childcare in our daycare center (if you have any questions, please contact UKF-Familienservice), child care during holidays

Health Promotion: Benefit from our attractive health offers. We offer regular online and face-to-face courses on nutrition, relaxation, sports and exercise.

Professional development: Internal and external training for your professional development

Any questions? Many answers can be found in our FAQs for new employees. If you have any further questions, please do not hesitate to contact us.

At TRR 379, we are actively committed to equal opportunities, diversity, belonging and inclusion. We believe that diversity in all its forms - be it gender, age, ethnic background, religion, sexual orientation, physical or mental abilities or other personal characteristics - enriches our scientific culture and enhances our ability to innovate. We are convinced that different perspectives and experiences help us to develop the best solutions for our research initiative. Therefore, we explicitly invite people from the entire spectrum of diversity to apply. Your unique background and individual skills are a valuable contribution to our team. All applications are treated equally, regardless of personal characteristics, and equal opportunities are actively promoted.
Severely disabled applicants with equal personal and professional qualifications will be given preferential consideration. Please let us know about your personal requirements.

Join our team

Please use the time until August, 20 2024 to apply, stating the call number and a possible start date. For further information, please contact Prof. Dr. Andreas Chiocchetti at 069 / 6301 80658 or andreas.chiocchetti@med.uni-frankfurt.de .

Apply now
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